So, I was looking into trying some of the Python web frameworks this past weekend. I originally started to look into Django and TurboGears, but after seeing nxsy’s comparison, I decided to try Pylons. My initial thought was that all three have similar goals, but have different approaches. A decent Pylons book by James Gardner is available online, too. You can also get the dead tree version at Amazon.
A second reason that I wanted to try Pylons is that there is a well-known, real-world application written using Pylons. I think its a good thing to see how someone else uses a framework that you are evaluating. I may not want to copy their style, but it gives me great insight.